Out of all the people involved in creating the Marvel universe, Stan Lee may be the single most well-known.  He is also very actively involved in Marvel.  This involvement has even gone as far as making guest appearances in many of the TV shows, movies, and video-games that draw upon the Marvel universe, including Marvel: Ultimate Alliance 2, where Stan Lee made a guest appearance as one of the politicians who the main team of heroes had to save from the forces of a Titanium Man, who wanted to sabotage the discussions concerning the Superhuman Registration Act and turn it against the heroes.

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